Anesthesia Knowledge Test 24 (AKT-24) 2026 – 400 Free Practice Questions to Pass the Exam

Trisomy 18, also known as Edwards syndrome, has a notable gender distribution that favors females over males. This condition is characterized by the presence of an extra 18th chromosome and is associated with a variety of severe health issues and developmental challenges. Epidemiological studies have shown that the prevalence of Edwards syndrome is higher in females, with approximately 80% of cases occurring in females and only about 20% in males.

This difference in gender distribution is thought to be related to the higher prenatal mortality in males with the condition. As a result, when looking at live births, one will observe a greater number of females affected by Trisomy 18 compared to males. The understanding of this gender imbalance is critical for both genetic counseling and understanding the pathophysiology of the syndrome.